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BX912
Description of:BX912
BX-912 is a inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1).
Theoretical analysis:
M.Wt: ...
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WYE125132
Description of:WYE 125132
WYE-132 inhibited mTORC1 and mTORC2 in diverse cancer models in vitro and in vivo. Importantly,consistent with geneti...
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依維莫司|Everolimus
Description of:Everolimus依維莫司
Everolimus (RAD001) also known as SDZ-RAD, Certican, Zortress, Afinitorm is MTOR inhibitor with IC50 of 0.63 nM.<...
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Rapamycin
Description of:Rapamycin
In vitro, rapamycin inhibited the proliferation of primary bone marrow cells induced by IL-3, GM-CSF, KL, or a complex...
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AZD8055
Description of:AZD8055
In vitro, AZD8055 potently inhibits proliferation and induces autophagy in H838 and A549 cells.In vivo, AZD8055 induces ...
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OSI-027
Description of:OSI-027
OSI-027 binds to and inhibits both the raptor-mTOR (TOR complex 1 or TORC1) and the rictor-mTOR (TOR complex 2 or TORC2)...
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PP242
Description of:PP242
PP242 inhibits other PI 3-Kinases only at much higher concentrations. PP242, but not rapamycin, causes death of mouse and ...
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WYE-354
Description of:WYE-354
WYE-354,a cell-permeable pyrazolopyrimidine compound,is a potent and ATP competitive inhibitor of mTOR (IC50 = 5 nM), wi...
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Torin 2
Description of:Torin 2
Torin2 is potent and selective mTOR inhibitor (IC50 = 2.1 nM). Torin2 displays 800-fold cellular selectivity for mTOR ov...
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Torin1
Description of:Torin1
Torin1 is potent and selective mTOR inhibitor (IC50 = 2 - 10 nM for mTORC1 and mTORC2). Torin1 displays 200-fold selectiv...
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Antibody-drug Conjugate/ADC Related
AMPK
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